Beta-Oxymaslyanaya Kislota
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Beta-oxymaslyanaya kislota is a chemical compound found in the blood and urine of diabetics, first isolated by Stadelmann. It is formed in the body, mainly in the liver, from fatty acids and some amino acids, particularly when there is a deficiency of carbohydrates in the diet or poor carbohydrate absorption.
Encyclopedia entry (1928–1936)
BETA (/3)-OXIMASLYANAYA KISLOTA, CH3-CH(OH)-CH2-COOH, occurs in the form of a levorotatory modification, mainly in the blood and urine of diabetics; from the latter it was first isolated by Stadelmann. Its significance in diabetic acidosis was clarified by Magnus-Levy. Usually in syrup form, it can crystallize; it is determined by extraction with ether or oxidation with chromic mixture. B.-o. k. is formed in the body along with acetoacetic acid and acetone (ketone or acetone bodies, see), mainly from fatty acids, as well as from certain amino acids; the place of formation is the liver. Beta-oxymaslyanaya kislota is formed with a deficiency of carbohydrates in food or with their insufficient absorption. In small amounts, it is also formed normally, but mostly in diabetic coma.
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“Beta-Oxymaslyanaya Kislota.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/beta-oxymaslyanaya-kislota/