Cezol
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Cezol is a chloromethylate of nicotinic acid methyl ester, historically used in medicine to stimulate salivation, reduce thirst in diabetes insipidus, and resolve exudates and edema. The article details its administration dosages and its veterinary use for treating colic in horses.
Encyclopedia entry (1928–1936)
CEZOL, the chloromethylate of the methyl ester of nicotinic acid; at present it is replaced by neocezol, the bromomethylate of the methyl ester of N-methylhexahydropyridine-/J-carboxylic acid. Colorless crystals, soluble in water, sparingly soluble in alcohol, melting point 195-197°. It is proposed for stimulating salivation and reducing thirst in diabetes insipidus, and for the resorption of exudates and edema. Internally 0.05 2-3 times a day, subcutaneously 0.025-0.05 in an aqueous solution (1 cm3). In veterinary practice, it is used for colic in horses at 0.8 in 5 cm3 of an aqueous solution.
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Cite this page
“Cezol.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/cezol/