SULFATIDES

Biochemistry, Anatomy, Neurology

Also known as: sulphatides

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Sulfatides are substances found in brain tissue that are chemically classified as lipoids. According to Levene, they can be considered analogs of phosphatides where the phosphoric acid residue is replaced by sulfuric acid, though other authors suggest they contain both sulfuric and phosphoric acid residues.

Encyclopedia entry (1928–1936)

SULFATIDES, substances that are part of brain tissue and, according to their chemical properties, are classified as lipoids. There are no exact data in the literature regarding their structure. According to Levene, they can be considered as analogs of phosphatides, in which the phosphoric acid residue is replaced by sulfuric acid. The sulfatide isolated by Levene was dextrorotatory and melted at 210°. According to other authors, S. contain in addition to sulfuric acid also a phosphoric acid residue and are thus phospholipoids. The ratio of P and S in them is 1:1. Among the products of hydrolysis of S., cerebronic acid and aminoethyl alcohol have also been found.

Cite this page

“SULFATIDES.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/sulfatides/