Thallin

Pharmacology, Toxicology, History of Medicine

Also known as: Thallinum

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Thallin is a chemical compound formerly used as an antiseptic and antipyretic agent. It was typically administered as the sulfate salt but has been discontinued due to adverse side effects.

Encyclopedia entry (1928–1936)

THALLIN, Thallinum, tetrahydro-p-quinazoline. Was most commonly used in the form of the sulfate salt, Thallinum sulfuricum (C10H13NO)2.H2SO4. Thalline base - crystalline, whitish-yellow powder, with a spicy, coumarin-like odor and taste, soluble in 7 parts of cold water. Melts at 42°. Oxidizers cause intense green coloring in solutions. Acts as an antiseptic and antipyretic. Dose 0.1-0.5. The antipyretic action of Thallin is not prolonged, although its antipyretic effect is four times greater than that of antipyrine. Due to side effects (vomiting, cyanosis, hematuria, collapse), it is no longer used. Externally in 72% solutions as an antiseptic.

Cite this page

“Thallin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/thallin/