Wildbolz Reaction
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
The Wildbolz reaction is a diagnostic test for active tuberculosis where a patient's own urine is injected intradermally, causing an inflammatory response similar to tuberculin testing. The test involves processing the patient's urine by evaporating it to one-tenth of its volume and filtering it through a carbolic acid-treated solution before injection.
Encyclopedia entry (1928–1936)
WILDBOLZ REACTION (Wildbolz), or auto-urine test. If a tuberculosis patient is injected intradermally with his own urine, then within 48 hours an infiltrate with inflammatory redness forms, as occurs after tuberculin injection. The urine for producing the W. r. is evaporated in a vacuum at 65-70° to one-tenth of its volume, freed from salts by filtering through a filter moistened with 2% carbolic acid, and injected in the amount of 0.1 cubic cm (1-2 drops). According to Wildbolz, a positive reaction is a diagnostic sign of active tuberculosis and is caused by specific substances originating from tubercle bacilli or tuberculous tissue. Verification of Wildbolz's data by other authors gave contradictory results.
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Cite this page
“Wildbolz Reaction.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/wildbolz-reaction/