Pyrenol
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Pyrenol is a mixture of sodium benzoate and sodium salicylate with small amounts of benzoic acid and thymol, used as an antipyretic and anti-neuralgic agent for conditions like influenza, rheumatism, and neuralgia. The article notes that Pyrenol and its derivative Neopyrenol offer no therapeutic advantages over their individual components.
Encyclopedia article (1928–1936)
Pyrenol, Pyrenol, Pyranum, consists of a mixture of 48% sodium benzoate and 48% sodium salicylate, to which are added 2% each of benzoic acid and thymol, supposedly fused together. According to Zernik, Pyrenol is a mixture of equal parts of sodium salicylate and sodium benzoate and 0.2% thymol. Pyrenol is a white, sweetish powder with a light aromatic odor, soluble in water and alcohol. Its pharmacological action is explained by the presence of salicylic and benzoic acids. Pyrenol is used as an antipyretic and anti-neuralgic agent in influenza, rheumatism, postoperative bronchitis, neuralgia, asthma, and whooping cough. Dose: 0.1-0.5-2.0. The Pyrenol preparation Neopyrenol is a mixture of benzoic acid, sodium benzoate, and sodium oxybenzoate with thymol dissolved in paradixoybenzene, also of undefined composition, like Pyrenol. Its application and dosage are the same as Pyrenol. Side effects of Pyrenol and Neopyrenol: nausea, occasionally vomiting, profuse sweating. Pyrenol is contraindicated in cases of increased acidity and hemoptysis. Pyrenol and Neopyrenol offer no advantages in therapy compared to their constituent parts.
Related articles
Cite this page
“Pyrenol.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/pyrenol/