Stypticin

STYPTICIN, Stypticinum, s. Cotarninum hydrochloricum, cotarnin hydrochloride, colorless, easily soluble crystals. Cotarnin - oxymethylhydrastine - is obtained from the oxidation of narcotine. In its action, it is similar to hydrastinine. The difference is that, according to Falk, cotarnin does not cause vasoconstriction and does not enhance cardiac function. According to other authors (Kehrer), the vasoconstrictive effect is particularly pronounced with local application. Its effect on the uterus, according to Keshni, is somewhat weaker than that of hydrastinine. It is used as a hemostatic for bleeding, especially uterine bleeding, 3-5 times a day at 0.025-0.05. Subcutaneously, 5-10% solutions are used. Locally for parenchymal bleeding (urology, dental practice) in a 2% solution and in the form of cotton wool soaked in a 30% solution. For skin diseases - in the form of a 5% ointment. Phthalic cotarnin is called Styptol - a yellow powder that dissolves easily in water; it acts as a hemostatic.