Acetopyrin
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Acetopyrin is a compound of aspirin with antipyrine, a white crystalline powder with weak acetic acid odor. It functions as an antipyretic, anti-rheumatic, and anti-neuralgic agent, serving as a substitute for antipyrine and aspirin.
Encyclopedia entry (1928–1936)
Acetopyrin, acopyrin, Antipyrinum acetylosalicylicum, a compound of aspirin with antipyrine, a white crystalline powder with weak acetic acid odor; melting point 63-65°; dissolves in 20 parts of 2% solution of sodium bicarbonate, in 30 parts of hot water and in 400 parts of cold water; easily soluble in alcohol and chloroform, difficultly in ether; dissolves slowly in gastric juice; due to this it does not irritate the stomach like antipyrine; in the intestine it decomposes into antipyrine, salicylic and acetic acids. In urine after taking A. salicylic acid is found. Antipyretic, anti-rheumatic and anti-neuralgic remedy; used as a substitute for antipyrine and aspirin. Dosage of A.: 0.5-1.0, 3-6 times a day.
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Cite this page
“Acetopyrin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/acetopyrin/