Altmann-Schridde Granulation
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Altmann-Schridde granulation is a fuchsinophilic granulation found in lymphocytes, typically appearing as 20 to 25 short rods mainly in the perinuclear zone. Considered specific to lymphocytes, these structures can also be found in monocytes and myeloblasts, though usually in greater numbers and without a rod-like shape. The granulation is demonstrated using 1% osmium tetroxide fixation and Altmann's staining method.
Encyclopedia entry (1928–1936)
ALTMANN-SCHRIDDE GRANULATION (Altmann, Schridde), fuchsinophilic granulation found in lymphocytes in the form of 20-25 short rods, mainly in the perinuclear zone, and considered specific to lymphocytes. In monocytes and myeloblasts, fuchsinophilic formations are also encountered and even in a much larger number, but here they usually do not have a rod-like shape. Altmann-Schridde granulation is detected after fixation with 1% osmium acid and staining according to Altmann (see Altmann's methods).
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Cite this page
“Altmann-Schridde Granulation.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/altmann-schridde-granulation/