Deamidases

Biochemistry, Physiology

Also known as: Desamidases

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Deamidases are enzymes that cleave the amino group from chemical compounds and replace it with a hydroxyl group, causing true deamination. The article describes true deamidases such as guanase and adenase, noting that the deamination of amino acids involves oxidation-reduction processes rather than purely hydrolytic action.

Encyclopedia entry (1928–1936)

DEAMIDASES, enzymes that cleave the amino group from carbon-chain compounds with its replacement by a hydroxyl, i.e., causing deamination in the precise sense of the word. True deamidases are, for example, guanase and adenase—enzymes that deaminate the aminopurines guanine and adenine. The action of enzymes that deaminate amino acids is apparently not purely hydrolytic, but is associated with oxidation-reduction processes.

Cite this page

“Deamidases.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/deamidases/