Soviet Medical Encyclopedia

Decholin

Pharmacology

Also known as: Sodium dehydrocholate

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Decholin is the sodium salt of dehydrocholic acid, used as a powerful cholagogue and diuretic, especially in liver diseases. It was administered intravenously or orally in the 1930s.

Encyclopedia entry (1928–1936)

DECHOLIN, Decholin, the sodium salt of dehydrocholic acid, C23H33O3COONa; a colorless amorphous powder, readily soluble in water, sparingly in alcohol. Dehydrocholic acid, especially its sodium salt, exerts a powerful cholagogue effect; it is less toxic than other bile acids; in addition, dehydrocholic acid enhances diuresis, particularly in liver diseases. It is used intravenously in the form of a 5-20% aqueous solution (pro dosi 0.25-0.5-0.75), and internally in tablets (0.25 each), 2-3 times a day.

Cite this page

“Decholin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/decholin/