Fuadin

_fuadin, Fuadin, Neoantimosan, the antimony-sodium salt of 3,4-disulfopyrocatechol, Stibium-Natrium pyrocatechindisulfonicum. Named in honor of the Egyptian king Fuad, it is a modified Antimosan in which potassium is replaced by sodium. Formula: C₁₀H₄O₈SbNa₂·3H₂O·Na₂SO₄. Fuadin is easily oxidized in the air, but it is less toxic, better tolerated than Antimosan, and does not cause side effects. It is available as a sterile transparent 7% solution of greenish color: 1) in ampoules from 0.5 to 5 cm³, which oxidizes easily in the air; 2) in bottles from 25 to 100 cm³, "Fuadin stabilized", which does not oxidize in the air.

It is used as a specific agent for bilharziasis (Khalil, Tootell). Attempts have been made to use it for a number of other extraintestinal helminthiases in humans and animals (Distoma hepaticum, Schistosoma haematobium, Opisthorchis felineus). A good effect has been described in the treatment of trypanosomiasis, leishmaniasis, and encephalitis. Dosage of fuadin: intramuscularly, the initial dose for adults is 1.5 cm³, the second dose is 3.5 cm³, and subsequent doses are 5 cm³ each. The first 2 injections are given daily, the subsequent ones at intervals of 2 days. The full course of treatment for adults is 40-50 cm³. For children, the initial dose is 0.5 cm³, the second is 1.5 cm³, and subsequent doses are 3.5 cm³ each. The full course is up to 30 cm³.