Isoreactions

Microbiology, History of Medicine

Also known as: Isoimmune reactions, Serum isoagglutination

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Isoreactions are serum reactions where both antibody and antigen belong to the same animal species, differing from hetero-reactions where they have different origins. These reactions are characteristic of normal human serum and show specificity when is antibodies encounter corresponding antigens.

Encyclopedia entry (1928–1936)

ISOREACTIONS, serum reactions, in which both the antibody and the antigen belong to the same animal species. In this way, isoreactions differ from ordinary hetero-reactions of immunity, where the antigen and antibody have different species origins. Isoreactions are characteristic of normal human serum and exhibit clear specificity, expressed in the fact that an isoreaction occurs only when the is antibody of the serum encounters its corresponding antigen (Landsteiner). Among I., the reaction of isoagglutination has acquired the greatest theoretical and practical significance (see Agglutination). ISOTELA

Cite this page

“Isoreactions.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/isoreactions/