Jakob

JAKOB Alfons (Alfons Jakob, 1884-1931), a prominent German neuropathologist. In 1911, J. became head of the anatomical laboratory in Hamburg, and from this time began his fruitful activity, which earned him worldwide fame. J. authored 75 scientific works and more than 150 works by his students, in which he himself actively participated. The series of J.'s works begins with a dissertation on the pathogenesis of pseudobulbar paralysis and a work on psychoses developing on the basis of circulatory disorders. In 1912_4- he wrote a monograph on secondary degeneration and conducted experimental research on traumatic brain injury. After the imperialist war, he began to systematically study syphilis of the nervous system, resulting in his major works on stationary and atypical forms of syphilis, syphilitic endarteritis, etc. His famous monograph on extrapyramidal diseases dates from 1923. J. authored two extensive and exhaustive articles on the morphology of the cerebellum, published in Mellendorff's microscopic anatomy of the nervous system, and on syphilis of the brain, in Bumke's textbook of psychiatry. In addition, Jakob wrote two volumes on the anatomy and histology of the cerebrum, with the second volume being particularly valuable, containing chapters on tuberculosis, multiple sclerosis, and syphilis of the cerebrum.