Zymophoric Group
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
The zymophoric group is a term introduced by Ehrlich in his side-chain theory to describe the functional component of a receptor that induces specific changes in a bound antigen. According to the theory, receptors of the second order possess both a haptophoric group for binding and a zymophoric group responsible for the subsequent reaction, such as agglutination.
Encyclopedia entry (1928–1936)
ZYMOPHORIC GROUP, a term introduced by Ehrlich in his side-chain theory. According to Ehrlich, a receptor of the second order possesses a haptophoric and a zymophoric group: the first brings about the attachment of the antigen to the antibody, while the second causes definite changes in the attached antigen; for example, an agglutinin (receptor) bears a haptophoric group that binds it to the antigen (agglutinogen) and a zymophoric group that causes agglutination.
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“Zymophoric Group.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/zymophoric-group/