Bardet Syndrome

BARDET SYNDROME (Bardet), consists of phenomena of general obesity, hypogenitalism, polydactyly, sometimes - brachydactyly and pigmentary retinitis. B. s. is most often a familial condition, detected usually in childhood. The symptoms included in B. s. may also be observed separately in members of corresponding families. Bardet, Chaillons consider the syndrome a consequence of combined lesions of the hypophysis and retina. Pende also points to the presence of hypopituitarism in B. s.; conversely, Biedl, who described this syndrome later, explained it by the presence of abnormalities in skull development, with subsequent disturbance of function from the diencephalon. Others see in B. s. a peculiar correlation in a series of anomalies of a genotypic nature.