BEBERINE
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Beberrine is a tertiary base containing an isoquinoline ring, isolated from Nectandra Rodiaei and Chondodendron tomentosum. It was thought to have quinine-like effects against malaria, though this was not proven.
Encyclopedia entry (1928–1936)
BEBERINE, Bebirinum (syn.: oeberine, oe-berine, pelozin), C18H21NO3, a tertiary base, apparently containing an isoquinoline ring. Isolated in pure form in 1898 by M. Scholtz. Obtained from the bark of Nectandra Rodiaei (family Lauraceae) and from the root of Chondodendron tomentosum (family Menispermaceae). A crystalline powder, sparingly soluble in alcohol and ether, easily soluble in methyl alcohol and chloroform, melting point 214°. Rotates the plane of polarization to the left. The hydrochloride and sulfate salts of B. are colorless needle-shaped crystals; those in commerce often appear as colored scales. B. was attributed a quinine-like action against intermittent fever (however, this was not proven); doses from 0.05 to 0.1, three to four times a day.
Related articles
Cite this page
“BEBERINE.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/beberine/