Butolan
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Butolan is a carbamic acid ester of benzylphenol, used in the 1930s as an anthelmintic medication particularly effective against pinworms. The drug acts after saponification in the intestines and is administered in divided doses followed by a laxative.
Encyclopedia entry (1928–1936)
BUTOLAN, the carbamic acid ester of benzylphenol (para-oxydiphenylmethane), consists of colorless crystals, odorless and almost tasteless, sparingly soluble in cold water, readily soluble in hot water, benzene, and ethyl acetate, as well as in alkalis. The action of the preparation begins after the saponification of butolan in the intestines. It is used against intestinal worms, especially pinworms. Dose: 0.5 three times a day; after a three-day course, a laxative is given.
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Cite this page
“Butolan.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/butolan/