Folliculin

Folliculin, a preparation corresponding to the hormone that causes estrus. F. is manufactured from the urine of pregnant women, in which this hormone ('ovarian hormone') is present in large quantities. F. corresponds to the following preparations: menformon, estrin, progynon, folliculin, and others. F. is standardized by the Allen and Doisy method (see Ovarin) and is released in ampoules containing 40 mouse units per 1 cm³. F. is used in infantilism, hypoplasia of female sexual organs, virilism, amenorrhea and oligomenorrhea, early climacteric, disturbances of blood formation during the period of puberty in girls (chlorosis, anemia), in hypogenital obesity, skin diseases associated with sexual maturity, nervous diseases, as well as in arthritides associated with insufficient function of the sex glands. The average dose of F. is considered to be 40-80 units per day, subcutaneously. For special indications, 200-300 units per day are used. The 'Farmakon' factory manufactures F. with a content of 250-1,000 mouse units in 1 cm³.