Gynergen

GYNERGEN, Gynergen, 0.05% solution of vinic tartaric acid ergotamine, an alkaloid from ergot. Used for uterine atony after childbirth, for postpartum hemorrhage, at the beginning of cesarean section, after abortions, for climacteric bleeding. Dose 0.5-2 cubic cm subcutaneously. The pharmacological action of G. manifests itself in suppressing the sympathetic nerve and in stimulating the vagus. From this follows the use of G. in disease of Basedow, in which it reduces heart palpitations, perspiration, protrusion of the eyes, general weakness. In glaucoma, injection of G. reduces intraocular pressure. Side effects: occasionally vomiting, headache, tetanic contraction of the uterus (when used during childbirth); therefore it is prescribed not to be used during the period of uterine dilation and expulsion of the fetus. Dosage: after childbirth and during operations - 0.5-1.5 cubic cm subcutaneously. In disease of Basedow - 0.3-0.5 cubic cm 2-3 times a day, in glaucoma - 0.5 cubic cm 2-3 times a day. G. in tablets (containing 0.001 - 0.002 G.) is taken 2-3 times a day, 1 tablet each time.