Hyperadrenia

HYPERADRENIA, HYPOADRENIA, primarily clinical concepts that should denote states of the organism with increased (hyper-) or, conversely, decreased (hypo-) internal secretory activity of the adrenal glands. Since it is now firmly established that genetically, morphologically, and physiologically the adrenal glands represent formations consisting of two completely independent organs - the cortical and medullary (medullary) substance - the concepts of hyperadrenia and hypoadrenia cannot correspond to the essence of the processes occurring in the organism when adrenal function is impaired; therefore, it is more correct to use the terms hyper- and hypoadrenalism (medullary hyper- and hyposuprarenalism) and hyper- and hypocorticalism (cortical hyper- and hyposuprarenalism). The clinical pictures of adrenal syndromes cannot at the present time be considered sufficiently defined; this depends on the still insufficient (despite the many studies devoted to this question) knowledge of the mechanism of a number of vital humoral, endocrine-nervous (neurocrine) influences originating from the adrenal gland (see also Adrenaline, Adrenal glands).