Keratolysis

KERATOLYSIS (from Greek keras - horn and lysis - dissolution), dissolution and shedding of the horny layer by chemical substances, mainly alkalis or acids, of which the former have a more energetic effect. The main indications for keratolytic treatment are: a) hyperkeratoses (see), especially calluses, warts, ichthyosis; b) dermatoses with thickening of the horny layer, scaling or formation of follicular horny spines - Darier's disease, psoriasis, certain forms of eczema, acne, pityriasis rubra pilaris, etc.; c) onychomycoses; d) hypertrichoses. The main keratolytic agents used in the form of solutions, ointments, pastes, emulsions, lacquers, plasters - sulfur preparations, including sulfur waters, potassium soaps, especially green soap, alcoholic soap solution, saponin, decoction of Panama bark (75:1,000), resorcinol, acids, especially salicylic and lactic; various depilatories (see), caustic potash or soda. When using strong keratolytic agents, for example, a solution of caustic alkali, the surrounding healthy skin should be protected with paste or ointment (for example, zinc ointment).