Maretin
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Maretin is a chemical derivative (m-tolylsemicarbazide) historically used as an antipyretic and analgesic agent in the early 20th century. The article outlines its chemical structure, depressive effect on the central nervous system, therapeutic doses for conditions such as tuberculosis and rheumatism, and potential side effects.
Encyclopedia entry (1928–1936)
MARETIN (Maretin), CH3.C6H4.NH.NHCONH2, carbamic acid m-tolylhydrazide; a derivative somewhat resembling antifebrin, but with a weaker toxic effect. It exerts a depressant effect on the central nervous system, predominantly on the centers perceiving pain sensations and temperature regulation. Therapeutic application: as an antipyretic in fever (tuberculosis), typhus, pneumonia, and as a pain reliever in rheumatism, neuralgia, etc. Dose: 0.1-0.25 per dose, twice a day, for no more than 4-5 consecutive days. Side effects: collapse, profuse sweating, jaundice.
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Cite this page
“Maretin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/maretin/