Polynuclear

POLYNUCLEAR (from Greek polys - many and Latin nucleus - nucleus), "multinucleated" cell, a term used exclusively in reference to mature neutrophilic leukocytes, the nuclei of which consist of several fragments, which simulates multinuclearity. The term P. cannot be considered successful, since in essence the concept of multinuclearity of leukocytes is based on a misconception. The nucleus of a mature leukocyte is segmented and appears sometimes in the form of a cloverleaf, sometimes a dumbbell, and sometimes like a chain of 2-5 fragments connected by narrow bridges. The latter are so thin that often with coarse staining and superficial examination, a false impression may be created of the presence of several nuclei in the leukocyte. At present, the term P. is used less and less frequently. Some recommend replacing the term P. with more reality-conforming terms - "segmented" (Schilling) or "polymorphonuclear". The percentage content of polynuclear cells in the blood is on average 67% (from 60% to 75%). See also Hematopoiesis, Blood, Blood leukocyte formula, Leukocytes.