Soviet Medical Encyclopedia

Quinidine

Pharmacology, Internal Medicine

Also known as: Chinidinum purum, Con-quinine

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Quinidine is a dextrorotatory isomer of quinine that is less toxic to the heart. It reduces the excitability and contractility of the heart muscle and is used to treat atrial fibrillation and flutter, frequent extrasystoles, and prolonged attacks of paroxysmal tachycardia.

Encyclopedia entry (1928–1936)

QUINIDINE (Chinidinum purum), or con-quinine, is the dextrorotatory isomer of quinine (see), which is less toxic to the heart than quinine. Quinidine (and quinine) lowers the excitability and contractility of the heart muscle, and its effect on heterotopic (secondary) centers is more pronounced than on the sinus rhythm. Quinidine is used for atrial fibrillation and flutter, frequent extrasystoles, and prolonged attacks of paroxysmal tachycardia.

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Cite this page

“Quinidine.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/quinidine/