Acidol

Pharmacology, Internal Medicine, Biochemistry

Also known as: Betaine hydrochloride

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Acidol is betaine hydrochloride, a crystalline substance containing 23.8% hydrochloric acid, used in the 1930s as a substitute for free hydrochloric acid in medical practice. It is stable in dry form but hydrolyzes in aqueous solutions, providing a convenient way to administer hydrochloric acid in powder or tablet form.

Encyclopedia entry (1928–1936)

ACIDOL, Acidol, betaine hydrochloride (see), containing 23.8% hydrochloric acid; colorless crystals that are readily soluble in water. In the dry state, Acidol is stable and does not release HCl even upon heating; in aqueous solution, it undergoes strong (up to 60%) hydrolytic splitting and is therefore equivalent to HCl in appropriate doses: 0.5 g of Acidol corresponds to 5 drops of the acid. It is used in place of HCl in doses of 0.5–1.0 g of powder or 1–2 tablets (0.5 g each) per wineglass of water. Acidol must be stored protected from moisture.

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Cite this page

“Acidol.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/acidol/