Acitrin
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Acitrin is the ethyl ester of phenyl-quinoline-carbonic acid, a yellow crystalline powder used as an anti-gout and cholagogue agent. It is slowly absorbed in the intestines, reducing the risk of sand and stone formation in the urinary tract.
Encyclopedia entry (1928–1936)
Acitrin, Acitrin, C9H5N(COOH)C2H5, ethyl ester of phenyl-quinoline-carbonic acid, ethyl ester of atophan (see), yellowish crystalline powder without odor or taste, melts at 61-62°; dissolves in water, easily dissolves in organic solvents and concentrated mineral acids. In the intestine it is only gradually broken down with the release of free acid; due to this, slow absorption of atophan occurs, and consequently the danger of formation of sand and stones in the urinary tract is reduced. Used as an anti-gout and cholagogue in doses of 0.5-1.0 (3-4 times a day); at the same time, it is recommended to introduce large amounts of plain or mineral water. Acitrinum compositum - tablets containing 0.5 A. and 0.0003 colchicine.
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Cite this page
“Acitrin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/acitrin/