Agurin
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Agurin is a double compound of theobromine-sodium and sodium acetate introduced in 1900 by Destree. It is a white powder with a salty-bitter taste, used as a diuretic and vasodilator for kidney inflammation, cardiac and renal edema, and for treating and preventing angina pectoris and cardiac asthma.
Encyclopedia entry (1928–1936)
Agurin, a name given by Destree to the double compound of theobromine-sodium and sodium acetate that he introduced into therapy in 1900, which was obtained by Impens: C7H7NaC4O6 + CH3COONa - Theobrominum natrioaceticum, a white powder, easily soluble in water, of a salty-bitter taste, with an alkaline reaction; easily decomposes in solutions. It is well tolerated by the stomach and does not irritate the kidneys; a single dose is 0.5-1.0, daily up to 3.0. It acts as a diuretic and dilates blood vessels. It is prescribed for inflammation of the kidneys, for cardiac and renal edema, as well as for the treatment and prevention of attacks of angina pectoris and cardiac asthma.
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“Agurin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/agurin/