Nitroscleran
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Nitroscleran is a physiological solution containing sodium chloride, disodium phosphate, dipotassium phosphate, and sodium nitrite. It is used for arteriosclerosis with high blood pressure and angina pectoris, with effects based on its vasodilating properties.
Encyclopedia entry (1928–1936)
Nitroscleran, Nitroscleran, a physiological solution consisting of 0.6% NaCl, 0.36% disodium phosphate, 0.2% dipotassium phosphate, and 2-4% sodium nitrite. The pharmacodynamics of N. are based on its content of sodium nitrite, which dilates blood vessels, accelerates the pulse, and decreases arterial tension. N. is used in cases of arteriosclerosis with elevated blood pressure and in angina pectoris. Dosage: intravenously - once daily an ampule containing 0.02, 0.04, and up to 0.1 sodium nitrite. Orally, granulated powder of N. is used in 1/4 teaspoon doses per administration (which corresponds to 0.05 sodium nitrite), 2-3 times daily. The side effects of N. are the same as those of sodium nitrite.
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Cite this page
“Nitroscleran.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/nitroscleran/