Angiokeratoma
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Angiokeratoma is a rare skin lesion characterized by small, dark red or lead-gray tumors with rough surfaces, typically appearing symmetrically on the hands or feet. The condition is chronic, often beginning in childhood and persisting throughout life, with histological features showing telangiectasias of capillaries in the papillary layer followed by hyperkeratosis.
Encyclopedia entry (1928–1936)
ANGIOKERATOMA, vascular-keratous tumor (angiokeratoma Mibelli), a rare skin lesion, symmetrically located on the hands or feet in the form of small tumors, from the size of a hemp seed to a pea, dark red or lead-gray in color with a rough surface. The course of A. is chronic; appearing in childhood, they grow until the period of maturity and for the most part remain for a lifetime, worsening in winter. Three stages of the lesion are distinguished: 1) stad. vasculare - the appearance of barely noticeable small, round, bright red spots; 2) stad. naeviforme - the epidermis grows over the affected areas, and the aforementioned tumors form; 3) stad. verrucosum - warty formations of sharply convex shape. A. is considered a constitutional anomaly, inherited and associated with tuberculosis, which causes toxic paralysis of the vessels. Histologically, telangiectasias of capillaries of the papillary layer are noted, followed by hyperkeratosis.
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“Angiokeratoma.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/angiokeratoma/