Hyperkeratosis
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Hyperkeratosis is the excessive formation of horn substance in the epidermis, occurring due to both increased production of keratin and the accumulation of keratinized cells that are not normally shed. It can manifest as localized tumor-like growths in conditions such as chronic skin inflammation, hypertrophic processes, skin cancers, calluses, and other conditions involving increased proliferation of epidermal cells.
Encyclopedia entry (1928–1936)
HYPERKERATOSIS (from Greek hyper- excessively and keras- horn), excessive formation of horn substance in the epidermis. It occurs both due to increased production of keratin substance, and mainly from the fact that keratinized cells are not shed, as happens in normal conditions, but accumulate on the surface of the skin, sticking together. Hyperkeratosis sometimes manifests in the form of limited tumor-like growths, for example, in chronic inflammations of the skin, hypertrophic processes, skin cancers, calluses (keratoma palmare) and generally under conditions of increased multiplication of epidermal cells. A hyperkeratosis spread over the entire body is called ichthyosis (see).
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“Hyperkeratosis.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/hyperkeratosis/