Bismutogwi

Pharmacology, Infectious Diseases, Dermatology & Venereology

Also known as: Bismutum Bitartaricum, Bismuth Bitartrate

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Bismutogwi is an insoluble bismuth preparation introduced for syphilis treatment in 1921. It is a 10% oil suspension of acid bismuth tartrate containing 39.76% metallic bismuth, used intramuscularly for all forms of fresh and latent syphilis.

Encyclopedia article (1928–1936)

BISMUTOGWI, Bismutogwi (ГВИ -Гос. венерол, ин-т), Bismutum bitartaricum, refers to insoluble bismuth preparations introduced into the therapy of syphilis by Sazerak and Levaditi in 1921; it is manufactured in the USSR by Gosmedtorgprom; it is similar in composition and action to Theropyrum and Bismogenol; it represents a 10% oil suspension of acid bismuth tartrate with a content of 39.76% metallic bismuth. It is used intramuscularly for the treatment of all forms of fresh and latent syphilis, energetically causing the disappearance of spirochetes and RW reactions. In terms of strength of action, it occupies a place between mercury and salvarsan, being less toxic. Dosage: 0.5-0.6-0.75 cubic cm of the preparation per injection; the first five days it is injected daily, the second five days every other day, and the rest every two days. The course does not exceed 20-25 injections. For children, 1/2, 1/3, and 1/4 doses are used. Side effects: bismuth line on the gums, rarely stomatitis, albuminuria, muscle pains. Contraindicated in kidney diseases and tuberculosis.

Cite this page

“Bismutogwi.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/bismutogwi/