Goldflam Disease

Goldflam Disease (Goldflam), is characterized by excessive fatigue and rapid exhaustion, i.e., phenomena described under the name apocamnosis, as well as identified as a cardinal symptom in myasthenia gravis. This disease was first described by Erb (see Erb disease). In addition to the disease G., Goldflam described a number of other symptoms. 1) In diseases of the sciatic nerve: pain in the area of the sciatic nerve when bending forward from a standing position or when rising from a horizontal position with the feet dorsally fixed. 2) Goldflam and Eiler's (Euler) symptom in intermittent claudication: rapid pallor of the foot and lower leg when the affected lower limb is raised upward and intense hyperemia when it is lowered. This phenomenon apparently depends on increased excitability of the vasoconstrictors of small arteries and capillaries and insufficient blood supply to the lower limb.