Gulevich

GULEVICV, Vladimir Sergeevich (born in 1867), outstanding biochemist, known for his works on the study of extractive substances of brain, muscle, and other tissues. Graduated from the medical faculty of Moscow University in 1890. Worked in analytical chemistry under A. P. Sabaneev and in organic and biological chemistry under A. D. Bulyginsky at Kharkov University, and in 1901 he joined the same department at Moscow University, where he also taught a course in organic chemistry at the medical faculty. From 1908 to 1924, he held the chair of biological chemistry at the Higher Women's Courses (now 2nd Moscow State University). Since 1910, he has been professor of organic chemistry at the Commercial Institute (now the Plekhanov Institute of National Economy) and president of the Association of Scientific Research Institutes at the Physics-Mathematics Faculty of 1st Moscow University, while being a member of many societies. Gulevich - full member of the Academy of Sciences of the USSR in the division of biology since 1928, as well as a member of the Leopoldina German Academy of Natural Sciences (also since 1928). The main works of Gulevich are devoted to the chemistry of the brain (monograph "On Choline and Neurine", Moscow, 1896), and to the composition of muscle and generally tissue extracts. Gulevich established the presence of new substances in meat extract - carnosine, carnitine, and methylguanidine. For the first time, he confirmed the presence of a β-amino acid in the organism (carnosine turned out to be β-alanyl-histidine). The total number of printed works by Gulevich, published mainly in Zeitschrift für physiologische Chemie, is about 60. From the laboratories he supervised, about 80 works emerged, many of which have a monographic character. Gulevich's book "Analysis of Urine" (Moscow, 1925) went through several editions, as did the "Brief Course of Biological Chemistry" compiled by I. A. Makeev based on Gulevich's lectures. 16 students of Gulevich hold chairs in various universities of the RSFSR and abroad.