Isamin Blue B
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Isamin Blue B is a blue powdered dye used for vital staining in laboratory animals. According to this 1930s encyclopedia article, it is administered subcutaneously to rats and mice to stain polyblasts and reticuloendothelial cells.
Encyclopedia entry (1928–1936)
ISAMIN BLUE B, 6 and R (Cassella), is a blue powdered dye that dissolves in water with a brilliant blue color. It is used for vital staining, for which a 1% solution of Isamin Blue in physiological saline is injected subcutaneously into rats and mice (1 cm3 per 20 g of body weight) 1-2 times a week until the skin turns blue. Sectioning is performed on a freezing microtome. The dye is deposited in polyblasts and reticuloendothelial cells.
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Cite this page
“Isamin Blue B.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/isamin-blue-b/