Methyl Violet
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Methyl Violet is a dye from the rosaniline group used as a nuclear stain in histology and bacteriology. It has metachromatic properties and is applied in various solutions for staining purposes, including as a substitute for gentian violet.
Encyclopedia entry (1928–1936)
METHYLVIOLETT (syn. Pyoctaninum coeruleum), methyl violet, a dye of the rosaniline group (see Histological Technique); depending on the number of methyl groups (the best grade is 6B - hexamethylpararosaniline), the intensity of staining varies. M. has the appearance of an amorphous or crystalline powder, easily soluble in water, alcohol, chloroform, giving a dark violet solution. A good nuclear stain; possesses pronounced metachromatic properties. For bacteriological purposes, it is widely used instead of gentian violet, especially Löffler's carbolic solution (10% solution of the dye in 1-2% solution of carbolic water) or Weigert's solution (concentrated solution of M. in 70% alcohol with the addition of 5% oxalic acid). For differentiation, alcohol or acids or alcohol after the application of Lugol's solution (according to Gram) is used. See also Fibrin.
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“Methyl Violet.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/methyl-violet/