Thermolabile

Biochemistry, Microbiology

Also known as: heat-labile, thermo-unstable

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

The term thermolabile refers to substances that are unstable and easily destroyed when heated. This concept is applied to various substances, vitamins, microorganisms, and plant seeds, with thermolability being relative and dependent on conditions like the presence of water or other chemicals.

Encyclopedia article (1928–1936)

Thermolabile, unstable with respect to heating; a term used to denote the property of various substances to easily decompose when heated by 1°. In contrast, substances that are stable to heating are designated as thermostable (heat-resistant). These same terms are often applied to microorganisms, especially their spores, as well as to plant seeds. Both concepts have extremely relative value and merely indicate greater or lesser resistance to heating of a given substance only in comparison with other substances of the same group. For example, vitamin C is called thermolabile as a substance that decomposes at a comparatively lower temperature than a number of other vitamins. Alexin (complement) is distinguished by its thermolability, which allows it to be separated from ambceptor, which withstands higher temperatures. The properties of thermolability and thermostability are not constant and depend on a number of conditions. For example, vitamin A is thermolabile when heated while simultaneously passing a stream of air, but when air is excluded, it can withstand temperatures up to 120°. The presence of water is also of great importance in terms of thermolability (rapid denaturation of proteins when heated in water and their stability in dry form), as well as the presence of various chemical substances.

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Cite this page

“Thermolabile.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/thermolabile/