TRIGEMIN
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Trigemin is a white crystalline powder used as an analgesic and sedative for headaches, toothaches, and trigeminal neuralgia. It has a melting point of 82-84°C and decomposes in air, becoming toxic when browned.
Encyclopedia entry (1928–1936)
TRIGEMIN (Trigeminum), pyramidon-butyl-chloralhydrate. A white crystalline powder with the odor of butylchloralhydrate, melting point 82-84° (chemically pure, anhydrous preparation melts at 85°), soluble in 65 parts water and 2 parts alcohol. Decomposes and browns in air. Used as an analgesic and sedative for headaches, toothaches, trigeminal neuralgia, etc., in doses of 0.25-0.5-1.0 g three times daily. According to some sources, the analgesic effect of Trigemin is stronger than that of pyramidon, phenacetin, and similar preparations. The browned preparation is poisonous, causing severe pain in the epigastric region and digestive disturbances.
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Cite this page
“TRIGEMIN.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/trigemin/