Vanler Phenomenon
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
The Vanler phenomenon, observed during nerve regeneration, describes the process where axons grow from the central stump to the peripheral end, restoring function. It also covers the use of inert bridges to replace nerve defects.
Encyclopedia entry (1928–1936)
Vanler Phenomenon (Vanler), observed during regeneration in a peripheral nerve and named by Vanler 'neurotization'; it consists of the following: after a long time following nerve transection, newly formed axonal cylinders originating from the central end of the segment begin to grow into the peripheral end, which plays a passive role of conductor, reach its terminal branches, after which the function of this nerve is restored. In an operative or traumatic defect in the nerve, the missing part of the nerve may be replaced by inserting between the ends of the nerve an indifferent substance (decalcified bone tube, compressed artery), which the nerve fiber uses as a bridge for the transition from the central end to the peripheral end.
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Cite this page
“Vanler Phenomenon.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/vanler-phenomenon/