Ziegler

Ziegler Ernst (Ernst Ziegler; 1849-1905), outstanding German pathologist. He graduated from the medical faculty of the University of Bern in 1872 and remained there as an assistant to the famous pathologist Klebs. In 1873, together with Klebs, he moved to Würzburg, where he worked at the pathological-anatomical institute as an assistant, first under the direction of Klebs, and then under the direction of Rindfleisch. In 1881 he was elected professor of pathological anatomy in Zurich, and in 1887 to a similar position in Tübingen. In 1889 he took the position of professor of general pathology and pathological anatomy in Freiburg, where he remained until his death. The most important scientific works of Z. and his school relate to inflammation, to tuberculosis and generally to the inflammatory neoplasm of tissue; here Z. and his students traced the fate of leukocytes in the inflammatory process, the origin of lymphoid cells and the so-called "polyblasts" (a term introduced by Z.), the development of fibroblasts, etc.; with respect to tuberculosis, the histogenesis of the tubercle and its cellular forms was traced. A number of important works by Z. relate to the pathological anatomy of rickets. Z.'s textbook on general pathology and pathological anatomy enjoyed enormous fame and was translated into Russian, French, Italian, and English. Z. founded the journals: "Beiträge zur allgemeinen Pathologie und pathologischen Anatomie" (now bearing Z.'s name) and "Centralblatt für allgemeine Pathologie und pathologische Anatomie", which continue to be published to this day. Z.'s popularity as a teacher and leader of scientific work was very great. From all countries, especially from Russia, America, and Japan, doctors came to the institute to Z. for advanced study in pathological anatomy and for scientific work. Among Russian scientists, who went through Z.'s school were Podyvysotsky, Ushinsky, Nikiforov, Melnikov-Razvedenkov, Vlasov, Chistovich, Maksimov, Shueninov, Berezovsky, and others.