Antithrombin
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
This historical article discusses antithrombin as substances in blood plasma that prevent intravital blood clotting in vessels. It describes their dual action in inhibiting thrombin formation from prothrombin and inactivating ready-made thrombin.
Encyclopedia entry (1928–1936)
ANTITHROMBIN, substances contained in blood plasma that prevent intravital blood clotting within vessels. Their action is twofold: they inhibit the formation of thrombin from prothrombin and inactivate ready-made thrombin. Antithrombins apparently belong to the phosphatides. The content of antithrombin in the blood is especially high after an intravenous injection of albumoses.
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“Antithrombin.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/antithrombin/