Bergonie Law
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
The Bergonie Law establishes that the radiosensitivity of cells depends on their ability to multiply, the duration of their karyokinetic process, and their degree of morphological and functional differentiation. This law forms the basis for the application of X-rays in general treatment, particularly for malignant tumors.
Encyclopedia entry (1928–1936)
Bergonie Law (Bergonie), establishing the radiosensitivity of cells, is based on the fact that not only different tissues, but also different cells making up any single tissue (and even the same cells at different moments of their development), respond differently to X-rays. The Bergonie (and Tribondeau) Law establishes that the radiosensitivity of cells is greater, 1) the greater their ability to multiply, 2) the longer their karyokinetic process continues, and 3) the less they are morphologically and functionally differentiated. The Bergonie Law forms the basis for the application of X-rays in treatment in general and malignant tumors in particular.
Related articles
Cite this page
“Bergonie Law.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/bergonie-law/