Hamartoma, Hamartia, Hamartoblastoma

Hamartoma, Hamartia, Hamartoblastoma (from Greek hamartano - I err, act incorrectly). Hamartia (hamartia) - a term proposed by E. Albrecht in 1904 to denote developmental defects of tissues consisting of an improper ratio of several tissues in a given location; most often it involves excessive development of one tissue to the detriment of another. Hamartias include certain birthmarks of the skin, based on congenital excessive development of blood vessels in that location (naevus vasculosus) or sebaceous glands (naevus sebaceus); also cases of congen excessive proliferation of neuroglia in the central nervous system (so-called glioses, gliomatoses), congen excessive development of respiratory bronchioles in the lung to the detriment of the actual lung parenchyma (see Bronchiectasis). In cases where hamartia appears as a prominent, isolated nodule resembling a tumor but without visible signs of progressive growth, it is referred to as a hamartoma. Hamartomas include certain types of angiomas (see), for example, congenital cavernomas of the liver, as well as congenital fibromas of the kidneys, chondromas of the lungs. Finally, if a true, progressively growing, sometimes malignant tumor develops from a hamartia or hamartoma, it can be called a hamartoblastoma.

7. Tagung, B., 1904; Herxheimer &., Gewebsmissbildungen (Die Morphologie der Missbildungen der Menschen u. der Tiere, herausgegeben v. G. Schwalbe, B. Ill, Jena, 1913).