Krehl

KREHL Ludolf (Ludolf Krehl, born in 1861), prominent German therapist and pathophysiologist. From 1886 to 1892 - assistant in the internal clinic in Leipzig under Wagner and Kuschmann. From 1892 - professor in Jena, Marburg, Greifswald, Tübingen, Strasbourg, and from 1906 - in Heidelberg, where he continues to work at the present time. K.'s early works relate to physiology and pathology of blood circulation and heat exchange. Of great interest are K.'s works in the field of heart pathology, collected by him in the monograph: "Die Erkrankungen des Herzmuskels und die nervosen Herzkrankheiten" (Special Pathology and Therapy, ed. by H. Nothnagel, Vol. XV, Part I, Issue 5, Vienna, 1901), explanations given by him together with Frey of the dicrotic rise of the pulse curve, reports on the possibility of cardiac hypertrophy of growth (together with Lommel), juvenile arteriosclerosis. "Pathological Physiology", a term first introduced by K. into the literature ("Pathologische Physiologie", 12th ed., Lpz., 1922; 2nd Russian ed.-SPB, 1900 and 1911), is widely known. The methodological approach of K. in the mentioned work is explicitly idealistic. In his later works and speeches, K. openly joins the vitalist camp, showing solidarity with von Uexküll, E. Hartmann, and others. In his work (1924) on disorders of thermoregulation and fever, he believes that "regulatory apparatuses work according to a definite plan", established for a predetermined result, and considers that "for their understanding other concepts are necessary than those existing at present in mechanistic biology". In 1928, in the work "Krankheitsform und Persönlichkeit" K. expresses hope that through further development of Freud's methodology it will be possible to advance toward understanding the absolutely unknowable. However, recognizing the successes achieved in understanding such processes, K. still believes that in them is hidden "something non-mechanical, which he must attribute to special psychic (mental) properties - seelische Eigenschaften - inherent in all living things". K. is editor of the journals "Deutsches Archiv f. klin. Medizin", "Schmiedebergs Archiv f. experimentelle Pathologie u. Pharmacologie". After the death of Meringh he edits the widely distributed and repeatedly reissued guide to internal diseases, published by the latter with the participation of many authors. Under the joint editorship of K. and Marchan appeared the monumental "Handbuch der allgemeinen Pathologie" (Vols. I-IV, Lpz., 1915-24).