Moebius Disease
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Moebius disease is a familial-hereditary condition characterized by isolated cranial nerve paralyses resulting from the death of ganglion cells in the respective cranial nerve nuclei. It often manifests clinically as congenital ptosis of one or both eyelids due to involvement of the levator palpebrae superioris muscle, alongside other forms of ophthalmoplegia. Because the condition is congenital, there is no specific treatment.
Encyclopedia entry (1928–1936)
MOEBIUS DISEASE (Moebius), isolated cranial nerve paralyses resulting from the destruction of ganglion cells in the nuclei of the corresponding cranial nerves; they are grouped under the name Kernschwund and represent a familial-hereditary disease. Clinically, it is most often expressed as congenital ptosis of the upper eyelid of one or both eyes due to paralysis of the levator palpebrae superioris muscle (see Children's Paralyses); in addition to the paralysis of this muscle, paralyses of other ocular muscles—ophthalmoplegia (see)—are also encountered. Since the disease is congenital, there is no specific therapy.
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Cite this page
“Moebius Disease.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/moebius-disease/