TERPENES

Biochemistry, Pharmacology

Also known as: Isoprenoids

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Terpenes are hydrocarbons with the empirical formula (C5H8)n, classified as hemiterpenes, monoterpenes, sesquiterpenes, and polyterpenes. In medicine, terpenes like camphor, menthol, and thymol are used in various pharmaceutical formulations similar to essential oils.

Encyclopedia entry (1928–1936)

TERPENES. Under the general name T. are understood hydrocarbons of the empirical formula (C5H8)n and accordingly they are divided into: 1) hemiterpenes, C5H8; 2) monoterpenes, C10H16; 3) sesquiterpenes, C15H24; 4) polyterpenes, (C5H8)n. Hemiterpenes, compounds with an open carbon chain, possess two ethylene bonds, are easily formed from more complex T. (turpentine, rubber, etc.) during dry distillation and conversely revert to T. upon their polymerization; a typical example is isoprene CH2 = C(CH3)-CH=CH2. Monoterpenes can be both natural, occurring in plants, and artificial, obtained by laboratory methods; in general, about 15-20 isomers are known. In medicine, representatives of T. (e.g. camphor, menthol, thymol) are used similarly to essential oils in capsules, ointments, plasters, liquids, oil solutions, sometimes per se.

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“TERPENES.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/terpenes/