Dissemination
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Dissemination refers to the spread of infectious agents from a local focus either within an organ or throughout the body via blood and lymphatic systems. This process often leads to generalization of the disease with multiple new foci, or changes in the body's immunobiological state causing allergies.
Encyclopedia entry (1928–1936)
Dissemination (from Latin disseminare - to scatter), dissemination, a term used to denote cases where from some local infectious focus there occurs a spread of the causative agents of the process both within one or another organ (e.g. bronchogenous dissemination of tuberculosis of the lungs), and throughout the body, via its blood and lymphatic systems. Following dissemination, usually, though not necessarily, there occurs a generalization of the process itself, i.e. the development of new, mostly numerous foci of the same (or similar in nature) process. If generalization of the process does not occur, dissemination still leads to a change in the immunobiological state of the body, to allergy (see Tuberculosis). It should however be noted that in both practical and theoretical medicine, the term dissemination is often used with the same meaning as the term 'generalization' (e.g. they speak of dissemination of tuberculosis, dissemination of a tumor, etc.).
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“Dissemination.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/dissemination/