Pellidol
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Pellidol is a derivative of azotoluol used in the 1930s for treating persistent wounds, burns, and weeping eczemas, particularly in infants. It was applied in 2-4% ointments, pastes, and powders, and also used in ophthalmology for keratitis and in gynecology for gonorrhea.
Encyclopedia article (1928–1936)
Pellidol, Pellidol, diacetyl-amido-azotoluol, belongs to the derivatives of azotoluol. Pellidol is a powder of yellowish-brick color, insoluble in water, easily soluble in alcohol, ether, chloroform, fats, and fatty oils. Similar to another derivative of azotoluol—scarlet red (amido-azotoluol-azo-/3-naphthol)—it promotes the growth of epithelium on wound surfaces and in skin lesions such as eczema, etc. The action of Pellidol amounts to reactive irritation of the diseased tissue. Some authors deny the epithelizing ability of pellidol. Pellidol does not stain tissues like other derivatives of aniline dyes. Pellidol is used for the treatment of persistent non-healing wounds, burns, and weeping eczemas, especially in infants, in 2-4% ointments, pastes, and powders; in ophthalmic practice—for the treatment of keratitis in 0.5-2% ointments with vaseline; in female gonorrhea—5% Pellidol in the form of urethral sticks. As a side effect, erythema of the skin is occasionally noted. The Pellidol preparation—azodolen (Azodolen)—is a mixture of Pellidol in equal parts with iodolen (protein iodine compound); indications and dosage are the same as for Pellidol.
Related articles
Cite this page
“Pellidol.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/pellidol/