Sabadilla

Pharmacology, Toxicology, History of Medicine

Also known as: Sabadilla officinarum, Schoenocaulon officinale, Veratrum officinale

Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.

Summary

Sabadilla is a perennial bulbous plant of the lily family native to Mexico and Venezuela, whose seeds contain alkaloids and have been used medicinally since the 18th century as a pediculicide. The article describes its botanical characteristics, chemical composition, historical medicinal applications, and preparations.

Encyclopedia article (1928–1936)

Sabadilla, Sabadilla officinarum Brandt., Schoenocaulon officinale Asa Gray, a perennial bulbous plant of the lily family, growing wild in Mexico and Venezuela, with narrow, long, linear leaves and a flowering stem reaching 1-2 meters in height. The fruit is a 3-celled, many-seeded, splitting capsule. In medicine, the seeds of S. ('louse seed') are used, of an oblong-lanceolate shape, yellow-brown in color, 5-9 mm in length and up to 2 mm in diameter. The seed contains over 5% alkaloids, of which the main active principle is considered to be crystalline verat-rip (see) or cevadine, then sabadine, sabadinine, sabatrine, crystalline veratric acid, and fatty oil. An alcoholic tincture of the seeds turns greenish with sulfuric acid, which changes to carmine-red upon heating. The seed, known in Europe since 1571, was introduced in the 18th century by Capuchin monks (Capuchin powder) against lice. It is used in the form of a decoction, so-called louse water, vinegar (Acetum. SSabadillae) (composition-10 parts of crushed seeds, 10 parts of 90% alcohol, 18 parts of 30% vinegar, and 72 parts of water), tincture (10% in alcohol) and ointment (20% from finely powdered seeds and vaseline). Sabadilla seeds and preparations from them are stored with caution and dispensed exclusively on prescription. Picture of sabadilla poisoning and antidote-see Veratrin.

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Cite this page

“Sabadilla.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/sabadilla/