Validol
Historical document, translated for reference. It reflects medical knowledge of the 1920s–30s and is not medical advice.
Summary
Validol is a syrup-like liquid composed of isovaleric acid menthol with 30% free menthol. It is insoluble in water but soluble in alcohol. The article describes its calming and anti-fermentative effects on the nervous system and lists its uses for various conditions, including heart neuroses, migraines, and alcohol poisoning.
Encyclopedia entry (1928–1936)
VALIDOL, Validol, isovaleric acid menthol with 30% free menthol. A syrup-like liquid, insoluble in water, soluble in alcohol. Due to its composition, it acts calming on the nervous system and is anti-fermentative. It is applied in heart neuroses, nervous dizziness, hysteria, migraine, nervous vomiting and nausea, at alcoholic poisoning, after anesthesia with brom-ethyl, at gastric crises, sea sickness, nervous dyspepsias and vomiting of pregnancy. Locally: in ointments (10%) for itching and pruritus; for rhinitis and catarrhs of the respiratory tract for inhalation. Dose: orally 5-10-15 drops 2-3 times a day on sugar, in sweet water or gelatin capsules. It is contraindicated in reflex vomiting (brain, uremic, etc.).
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“Validol.” Soviet Medical Encyclopedia. English translation of Bolshaya Meditsinskaya Entsiklopediya, 1st ed. (Moscow, 1928–1936), ed. N. A. Semashko. https://sovietmedicalencyclopedia.pages.dev/article/validol/